Jonathan Taylor Week 16 Preview vs. the 49ers

Jonathan Taylor has a decent matchup when his Indianapolis Colts face the San Francisco 49ers in Week 16 (Monday, 8:15 p.m. ET). The 49ers have given up 106.1 rushing yards per game, 12th in the league.

As part of the rushing attack, Taylor has carried the ball 272 times for a team-best 1,443 yards (103.1 ypg) and has 16 rushing TDs. Taylor has compiled 318 yards on 38 receptions (22.7 ypg) and two receiving TDs.

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Taylor vs. the 49ers

• Taylor vs the 49ers (since 2021): 1 GP / 107 RUSH YPG / 1 RUSH TD
• The 49ers have let just two opposing rushers to amass 100 or more yards in a game during the 2025 season.
• San Francisco has allowed eight opposing rushers to record one or more TDs on the groun against them this year.
• The 49ers have given up two or more rushing TDs to just one opposing rusher this season.
• Taylor will play against the NFL's 12th-ranked run defense this week. The 49ers concede 106.1 yards on the ground per game.
• So far this year, the 49ers have conceded nine passing TDs to their opponents, averaging 0.6 per game. That ranks fourth among NFL teams.

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Taylor Rushing Insights

• Taylor has hit the rushing yards over in seven of 14 opportunities (50.0%).
• The Colts have passed 54.5% of the time and run 45.5% this season. They rank sixth in the NFL in scoring.
• His team has attempted 372 rushes this season. He's taken 272 of those carries (73.1%).
• Taylor has a rushing touchdown in seven games this year, including multiple rushing TDs five times.
• He has 40.9% of his team's 44 offensive touchdowns this season (18).
• He has 58 red zone rushing carries (68.2% of his team's rushing attempts inside the red zone).

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Taylor's Recent Performance